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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-IEM-1754
IEM-1754

Chemical Structure : IEM-1754

CAS No.: 162831-31-4

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IEM-1754 (IEM1754)

货号: PC-27572Not For Human Use, Lab Use Only.

IEM-1754 is a selective antagonist of GluR2-lacking AMPA receptors (AMPAR) with KD of 12.0 uM (−80 mV), has >80-fold selectivity over GluR2-containing AMPAR.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

IEM-1754 is a selective antagonist of GluR2-lacking AMPA receptors (AMPAR) with KD of 12.0 uM (−80 mV), has >80-fold selectivity over GluR2-containing AMPAR.

物理化学性质&存储条件

分子量 412.25
分子式 C16H32Br2N2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N1-(adamantan-1-ylmethyl)pentane-1,5-diamine dihydrobromide

参考文献

1. Tikhonov DB, et al. Br J Pharmacol. 2000 Jan;129(2):265-74.

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