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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-IEM-1925
IEM-1925

Chemical Structure : IEM-1925

CAS No.: 258282-23-4

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IEM-1925 (IEM-1925 bromide, IEM1925)

货号: PC-27571Not For Human Use, Lab Use Only.

IEM-1925 is a selective antagonist of GluR2-lacking AMPA receptors (AMPAR) with KD of 1.1 uM (−80 mV), >100-fold selective over GluR2-containing AMPAR.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

IEM-1925 is a selective antagonist of GluR2-lacking AMPA receptors (AMPAR) with KD of 1.1 uM (−80 mV), has >100-fold selectivity over GluR2-containing AMPAR.

物理化学性质&存储条件

分子量 422.25
分子式 C17H30Br2N2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1,5-Pentanediamine, N1-(1-phenylcyclohexyl)-, hydrobromide (1:2)

参考文献

1. Tikhonov DB, et al. Br J Pharmacol. 2000 Jan;129(2):265-74.

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