| Cat. No. |
Product Name |
Information |
| PC-42832 |
PF-04217903
c-Met inhibitor
|
PF-04217903 is a potent, selective, ATP-competitive c-Met kinase inhibitor with Ki of 4.8 nM, inhibits HGF-stimulated tyrosine phosphorylation of wild type c-Met with IC50 of 7.3 nM in cell-based assays. |
| PC-42829 |
SU11274
c-Met inhibitor
|
SU11274 (PKI-SU11274) is a potent, selective, ATP-competitive c-Met kinase inhibitor with IC50 of 20 nM, >50-fold selectivity over Bcr-Abl, JAK2, PDGFβR. |
| PC-42814 |
PHA-665752
c-Met inhibitor
|
PHA-665752 is a potent, selective, ATP-competitive c-Met inhibitor with Ki/IC50 of 4/9 nM, inhibits c-Met RTK autophosphorylation in A549 cells with IC50 of 45 nM. |
| PC-60929 |
MET inhibitor Compound 1
c-Met inhibitor
|
MET inhibitor Compound 1 is a potent, selective orally bioavailable MET tyrosine kinase inhibitor with IC50 of <1 nM and 12 nM for unphosphorylated and phosphorylaed MET, respectively. |
| PC-60656 |
SOMG-833
c-Met inhibitor
|
SOMG833 (Zgwatinib) is a potent, selective, ATP-competitive c-MET inhibitor with IC50 of 0.93 nM. |
| PC-60463 |
SAR 125844
c-Met inhibitor
|
SAR 125844 is a potent, highly selective, ATP-competitive MET receptor tyrosine kinase inhibitor with IC50 of 4.2 nM. |
| PC-70080 |
Glesatinib
AXL/c-Met inhibitor
|
Glesatinib (MGCD-265) is a tyrosine kinase inhibitor that potently and selectively inhibits Met and Axl kinase. |
| PC-60074 |
Glumetinib
c-Met inhibitor
|
Glumetinib (SCC 244) is a novel potent and highly selective inhibitor of c-Met kinase with IC50 of 0.42 nM. |
| PC-45885 |
Crizotinib
c-Met inhibitor
|
Crizotinib (PF-02341066;PF-2341066) is a potent, selective, orally bioavailable, ATP-competitive inhibitor of c-Met catalytic activity with Ki of 4 nM. |
| PC-45842 |
Tivantinib
c-Met inhibitor
|
Tivantinib (ARQ-197) is a potent, selective, non-ATP-competitive inhibitor of c-Met with Ki of 355 nM. |
| PC-45841 |
JNJ-38877605
c-Met inhibitor
|
JNJ-38877605 is a potent, selective, ATP-competitive inhibitor of catalytic activity c-Met with IC50 of 4 nM. |
| PC-42535 |
Foretinib
c-Met inhibitor
|
Foretinib (XL880, GSK1363089, GSK089, EXEL-2880) is a potent, multikinase inhibitor that inhibits c-Met and VEGFR, also KIT, Flt-3, PDGFRβ, and Tie-2. |
