| Cat. No. |
Product Name |
Information |
| PC-43061 |
LDC1267
TAM receptor inhibitor
|
LDC1267 is a potent, highly selective TAM receptor (Tyro3, Axl and Mer) kinase inhibitor with IC50 of <5 nM/8 nM/29 nM for Tyro3, Axl and Mer, respectively. |
| PC-42994 |
UNC2025 hydrochloride
Mer/FLT3 inhibitor
|
UNC2025 is a potent, orally bioavailable Mer/FLT3 dual inhibitor with IC50 of 0.74/0.8 nM, 700-fold less active against Met compared to Mer. |
| PC-42993 |
UNC2025
Mer/FLT3 inhibitor
|
UNC2025 is a potent, orally bioavailable Mer/FLT3 dual inhibitor with IC50 of 0.74/0.8 nM, 700-fold less active against Met compared to Mer. |
| PC-62809 |
Axl-IN-21
|
Axl-IN-21 is a selective and potent inhibitor of wild-type Axl with IC50 of 2.2 nM. |
| PC-61780 |
TAM-IN-1
Mer/Axl inhibitor
|
TAM-IN-1 is a highly potent, macrocyclic inhibitor of Mer and Axl with Ki of <50 pM and 130 pM, respectively. |
| PC-61679 |
UNC-1062
Mer inhibitor
|
UNC-1062 is a potent and selective Mer kinase inhibitor with IC50 of 1.1 nM, Ki of 0.33 nM. |
| PC-61325 |
N-butylidenephthalide
|
N-butylidenephthalide (NSC 325307) is a natural compound derived from Angelica sinensis that inhibits malignant brain tumor growth in vitro and in vivo. |
| PC-60247 |
RU-302
TAM receptor inhibitor
|
RU-302 is a small molecule pan-TAM inhibitor that targets the TAM Ig1-Gas6 interface, blocks Gas6-dependent TAM activation. |
| PC-60246 |
RU-301
TAM receptor inhibitor
|
RU-301 (RU301) is a small molecule pan-TAM (Tyro3-Axl-Mer)) inhibitor that targets the TAM Ig1-Gas6 interface, blocks Gas6-dependent TAM activation. |
| PC-42292 |
CEP-40783
AXL/c-Met inhibitor
|
CEP-40783 (CEP40783, RXDX-106) is a potent and selective AXL/c-Met inhibitor with IC50 of 7 nM/12 nM. |
| PC-26514 |
CPL423
TAM/FLT3 inhibitor
|
CPL423 is a potent selective TAM family of receptor tyrosine kinases (TYRO3, AXL, MERTK) and FLT inhibitor with IC50 of MERTK (0.47 nM) and FLT3 (0.94 nM), inhibits AXL and TYRO3 with IC50 of 2.15 and 6.73 nM, respectively. |
| PC-24514 |
UNC8212
TAM kinases inhibitor
|
UNC8212 is a potent, selective inhibitor of TAM-family (TYRO3, AXL, and MERTK) tyrosine kinases with IC50 of 1.5 nM, 1.3 nM, and 6.7 nM for MERTK, AXL and TYRO3 respectively. |
