N-butylidenephthalide |CAS:551-08-6 Probechem Biochemicals

Chemical Structure : N-butylidenephthalide

CAS No.: 551-08-6

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N-butylidenephthalide (NSC 325307, Butylidenephthalide, 3-Butylidenephthalide)

货号: PC-61325Not For Human Use, Lab Use Only.

N-butylidenephthalide (NSC 325307) is a natural compound derived from Angelica sinensis that inhibits malignant brain tumor growth in vitro and in vivo.

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50 mg	￥880	In stock
100 mg	￥1280	In stock
500 mg		Get quote
1 g		Get quote

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生物&药学活性

N-butylidenephthalide (NSC 325307) is a natural compound derived from Angelica sinensis that inhibits malignant brain tumor growth in vitro and in vivo.
N-butylidenephthalide upregulates the expression of p21 and p27, decrease sphosphorylation of Rb proteins, causes cell arrest at the G0/G1 phase in GBM tumor cells.
N-butylidenephthalide inhibits the expression of Axl and reduces the migratory and invasive capabilities of GBM cells.
N-butylidenephthalide inhibits tumour growth and suppresses Axl expression in tumour models.

物理化学性质&存储条件

分子量	188.226
分子式	C12H12O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Phthalide, 3-butylidene- (6CI,7CI,8CI)

参考文献

1. Yen SY, et al. Oncogene. 2016 Apr 28;35(17):2156-65.

2. Lin PC, et al. J Neurochem. 2008 Aug;106(3):1017-26.

3. Tsai NM, et al. J Neurochem. 2006 Nov;99(4):1251-62.

N-butylidenephthalide (NSC 325307, Butylidenephthalide, 3-Butylidenephthalide)

生物&药学活性

物理化学性质&存储条件

参考文献

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N-butylidenephthalide (NSC 325307, Butylidenephthalide, 3-Butylidenephthalide)

生物&药学活性

物理化学性质&存储条件

参考文献

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