Chemical Structure : RU-302
CAS No.: 1182129-77-6
货号: PC-60247Not For Human Use, Lab Use Only.
RU-302 is a small molecule pan-TAM inhibitor that targets the TAM Ig1-Gas6 interface, blocks Gas6-dependent TAM activation.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥1280 | In stock | |
10 mg | ¥1980 | In stock | |
25 mg | ¥3280 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
大包装,大折扣!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
RU-302 is a small molecule pan-TAM inhibitor that targets the TAM Ig1-Gas6 interface, blocks Gas6-dependent TAM activation.
RU-302 effectively blocks Gas6-inducible Axl receptor activation with low micromolar IC50s.
RU-302 inhibits Gas6-inducible motility in Axl-expressing cell lines, and suppress H1299 lung cancer tumor growth in a mouse xenograft NOD-SCIDγ model.
分子量 | 475.53 | |
分子式 | C24H24F3N3O2S | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
(2-(((3,5-dimethylisoxazol-4-yl)methyl)thio)phenyl)(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methanone |
1. Kimani SG, et al. Sci Rep. 2017 Mar 8;7:43908.
备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright