| Cat. No. |
Product Name |
Information |
| PC-36066 |
RIPK2 inhibitor OD36
RIPK2 inhibitor
|
RIPK2 inhibitor OD36 is a potent, specific, ATP-competitive inhibitor of RIPK2 with IC50 of 5.3 nM, inhibits Tyr and Ser/Thr-directed activities of RIPK2. |
| PC-35793 |
GSK547
RIPK1 inhibitor
|
GSK547 (RIP1i, GSK'547, GSK 547) is a highly selective and potent inhibitor of RIP1 kinase that robustly targets RIP1 in vivo. |
| PC-35704 |
HS-1371
RIPK3 inhibitor
|
HS-1371 (HS1371) is a novel potent, ATP-competitive receptor-interacting protein kinase-3 (RIP3 or RIPK3 kinase) inhibitor with IC50 of 20.8 nM. |
| PC-35429 |
CSLP43
RIPK2 inhibitor
|
CSLP43 (RIPK2 inhibitor CSLP43) is a novel potent, ATP pocket-binding RIPK2 inhibitor with IC50 of 19.9 nM in ADPGlo assay, demonstrates inhibition of both the RIPK2-XIAP interaction, and of cellular and in vivo NOD2 signaling. |
| PC-35428 |
CSLP37
RIPK2 inhibitor
|
CSLP37 (RIPK2 inhibitor CSLP37) is a novel potent, ATP pocket-binding RIPK2 inhibitor with IC50 of 16.3 nM in ADPGlo assay, demonstrates inhibition of both the RIPK2-XIAP interaction, and of cellular and in vivo NOD2 signaling. |
| PC-63388 |
GSK-2982772
RIPK1 inhibitor
|
GSK-2982772 is a potent, selective, ATP competitive RIP1 kinase (RIPK1) inhibitor with IC50 of 16 nM. |
| PC-63258 |
RIPK2 inhibitor 1
|
RIPK2 inhibitor 1 is a novel potent, selective RIPK2 inhibitor with IC50 of 5-10 nM. |
| PC-62661 |
GSK-872
RIPK3 inhibitor
|
GSK-872 (GSK'872) is a potent and selective RIPK3 (receptor-interacting protein kinase-3) inhibitor with IC50 of 1.3 nM, inhibits RIPK3-mediated necroptosis. |
| PC-62633 |
RIPK1 inhibitor 22
RIPK1 inhibitor
|
RIPK1 inhibitor 22 is a highly potent, orally available, and brain-penetrating RIP1 kinase (RIPK1) inhibitor with pKi of 9.04. |
| PC-60549 |
GSK963
RIPK1 inhibitor
|
GSK-963 (GSK963) is a potent and selective inhibitor of RIP1 kinase (RIPK1) with IC50 of 29 nM in FP binding assays. |
| PC-70204 |
Sibiriline
RIPK1 inhibitor
|
Sibiriline is a specific competitive RIPK1 inhibitor with IC50 of 1.03 uM, 100-fold less potent for RIPK3. |
| PC-60160 |
RIPK2 inhibitor 8
RIPK2 inhibitor
|
RIPK2 inhibitor 8 is a potent, selective, orally available RIPK2 inhibitor with IC50 of 3 nM. |
