GSK-872 |CAS:1346546-69-7 Probechem Biochemicals

Chemical Structure : GSK-872

CAS No.: 1346546-69-7

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GSK-872 (GSK'872)

货号: PC-62661Not For Human Use, Lab Use Only.

GSK-872 (GSK'872) is a potent and selective RIPK3 (receptor-interacting protein kinase-3) inhibitor with IC50 of 1.3 nM, inhibits RIPK3-mediated necroptosis.

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥3280	In stock
100 mg		Get quote

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生物&药学活性

GSK-872 (GSK'872) is a potent and selective RIPK3 (receptor-interacting protein kinase-3) inhibitor with IC50 of 1.3 nM, inhibits RIPK3-mediated necroptosis.
GSK-872 interferes with receptor-mediated endocytosis, entry of HIV, and synaptic vesicle recycling.
GSK-872 attenuates rat nucleus pulposus (NP) cells death.

物理化学性质&存储条件

分子量	383.49
分子式	C19H17N2O2S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-5-benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-quinolinamine

参考文献

1. Das A, et al. Tumour Biol. 2016 Jun;37(6):7525-34.

2. Qiu X, et al. Cell Death Dis. 2015 Aug 27;6:e1864.

3. Chen S, et al. Apoptosis. 2017 May;22(5):626-638.

GSK-872 (GSK'872)

生物&药学活性

物理化学性质&存储条件

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GSK-872 (GSK'872)

生物&药学活性

物理化学性质&存储条件

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