| Cat. No. |
Product Name |
Information |
| PC-38430 |
Zastaprazan
Gastric H+/K+-ATPase inhibitor
|
Zastaprazan (JP-1366) is a potent selective inhibitor of gastric H+/K+-ATPase activity with IC50 of 16.7 nM, >400-fold selectivity over Na+/K+-ATPase activity. |
| PC-73426 |
Linaprazan glurate
Proton Pump inhibitor
|
Linaprazan glurate (X-842) is a proton pump inhibitor with potential for treatment of oesophagitis. |
| PC-72574 |
Verucopeptin
V-ATPase inhibitor
|
Verucopeptin (BS-1152) is a cyclodepsipeptide with notable antitumor potency, directly taregts ATP6V1G, a subunit of the vacuolar H+-ATPase (v-ATPase). |
| PC-72018 |
Hv1 inhibitor HIF
Hv1 channel inhibitor
|
Hv1 inhibitor HIF is a novel inhibitor of the voltage-gated proton channel Hv1 interacts with the Hv1 VSD in the up and down states. |
| PC-38295 |
2GBI
Hv1 channel inhibitor
|
2GBI (2-guanidinobenzimidazole) is a guanidine derivative that inhibits voltage-gated proton channel Hv1 by binding to the VSD from its intracellular side.. |
| PC-38294 |
YHV98-4
Hv1 channel inhibitor
|
YHV98-4 is a selective inhibitor of proton-selective ion channel Hv1 with IC50 of 0.7 uM. |
| PC-63544 |
Diphyllin
V-ATPase inhibitor
|
Diphyllin is a naturally potent vacuolar ATPase (v-ATPase) inhibitor with IC50 of 17 nM, potently inhibits the acid influx with IC50 of 0.6 nM. |
| PC-62959 |
AR-HO47108
gastric H+/K+-ATPase inhibitor
|
AR-HO47108 is a potent, selective acid pump antagonist (potassium-competitive acid blocker or P-CAB) that reversiblely inhibits gastric H+/K+-ATPase with pIC50 of 7.0. |
| PC-60826 |
TAK-438
H(+),K(+)-ATPase inhibitor
|
TAK-438 (Vonoprazan) is a novel potent, potassium-competitive acid blocker (P-CAB) that inhibits H(+),K(+)-ATPase activity in porcine gastric microsomes with IC50 of 19 nM at pH 6.5. |
| PC-60811 |
Tegoprazan
gastric H+/K+-ATPase inhibitor
|
Tegoprazan (CJ 12420, RQ-00000004, RQ-4) is a novel potent, highly selective, competitive and orally active inhibitor of gastric H+/K+-ATPase with IC50 of ranging 0.29-0.52 uM porcine, canine and human H+/K+-ATPases in vitro. |
| PC-45146 |
Esomeprazole sodium
Proton pump inhibitor
|
Esomeprazole sodium is a proton pump inhibitor that reduces stomach acid secretion by inhibition of the H+/K+-ATPase in the parietal cells. |
| PC-23331 |
Tenatoprazole
Proton pump inhibitor
|
Tenatoprazole (TU-199) is an orally active imidazopyridine-based proton pump inhibitor, inhibits gastric H+/K+-ATPase activity with IC50 of 6.2 uM, also inhibits glutathione peroxidase 1 (GPX1). |
