| Cat. No. |
Product Name |
Information |
| PC-60826 |
TAK-438
H(+),K(+)-ATPase inhibitor
|
TAK-438 (Vonoprazan) is a novel potent, potassium-competitive acid blocker (P-CAB) that inhibits H(+),K(+)-ATPase activity in porcine gastric microsomes with IC50 of 19 nM at pH 6.5. |
| PC-60811 |
Tegoprazan
gastric H+/K+-ATPase inhibitor
|
Tegoprazan (CJ 12420, RQ-00000004, RQ-4) is a novel potent, highly selective, competitive and orally active inhibitor of gastric H+/K+-ATPase with IC50 of ranging 0.29-0.52 uM porcine, canine and human H+/K+-ATPases in vitro. |
| PC-60077 |
Azeloprazole sodium
Proton pump inhibitor
|
Azeloprazole sodium is a novel potent, orally active proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM. |
| PC-60032 |
Azeloprazole
Proton pump inhibitor
|
Azeloprazole (E-3710, Z-215) is a potent proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM. |
| PC-45146 |
Esomeprazole sodium
Proton pump inhibitor
|
Esomeprazole sodium is a proton pump inhibitor that reduces stomach acid secretion by inhibition of the H+/K+-ATPase in the parietal cells. |
| PC-45310 |
Pantoprazole sodium
Proton pump inhibitor
|
Pantoprazole sodium (SKF-96022 sodium) is a proton pump inhibitor that inhibits gastric acid secretion. |
| PC-45309 |
Pantoprazole
Proton pump inhibitor
|
Pantoprazole (SKF96022, BY1023) is a proton pump inhibitor that inhibits gastric acid secretion. |
| PC-42384 |
Bamaquimast
Proton pump inhibitor
|
Bamaquimast (F-10126) is a potent, orally active proton pump inhibitor with anti-inflammatory and antiasthmatic properties. |
| PC-42413 |
Ilaprazole
Proton pump inhibitor
|
Ilaprazole (IY-81149) is a potent, orally active proton pump inhibitor that irreversibly inhibits H+/K(+)-ATPase with IC50 of 6 uM. |
| PC-42022 |
Vonoprazan
H(+),K(+)-ATPase inhibitor
|
Vonoprazan (TAK-438 free base) is a potent, oral potassium-competitive acid blocker (P-CAB) that potently inhibits H+,K+-ATPase with IC50 of 19 nM. |
| PC-26887 |
NZ-58
Hv1 channel inhibitor
|
NZ-58 is a small molecule inhibitor of the HV1 voltage-gated proton channel with IC50 of 8.5 uM, also potently blocks voltage-gated Na+ and K+ channels at 50 uM, acts as a pan-VSD (voltage-sensor domains) modulator. |
| PC-26556 |
Dexlansoprazole
Proton Pump inhibitor
|
Dexlansoprazole ((R)-Lansoprazole) is the R enantiomer of Lansoprazole, which is a proton pump inhibitor, also binds to NTF2L domain of G3BP1 with Kd of 11 uM, reduces SARS-CoV-2 nucleocapsid protein (N) binds G3BP1 and inhibits viral replication. |
