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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Proton Pump

Request The Product List ofProton Pump Proton Pump

Cat. No. Product Name Information
PC-27263

Keverprazan

Potassium-competitive acid blocker

Keverprazan (H008, Carenoprazan) is a small molecule potassium-competitive acid blocker (P-CAB), shows potent and continuous gastric acid inhibition effect.
PC-27262

Keverprazan hydrochloride

Potassium-competitive acid blocker

Keverprazan hydrochloride (H008, Carenoprazan) is a small molecule potassium-competitive acid blocker (P-CAB), shows potent and continuous gastric acid inhibition effect.
PC-27037

Cladoniamide A

V-ATPase inhibitor

Cladoniamide A is a reversible broad-spectrum antiviral targets the human V-ATPase VO domain, interferes with V-ATPase-dependent acidification of the host endolysosomal network thus preventing viral entry.
PC-26887

NZ-58

Hv1 channel inhibitor

NZ-58 is a small molecule inhibitor of the HV1 voltage-gated proton channel with IC50 of 8.5 uM, also potently blocks voltage-gated Na+ and K+ channels at 50 uM, acts as a pan-VSD (voltage-sensor domains) modulator.
PC-26556

Dexlansoprazole

Proton Pump inhibitor

Dexlansoprazole ((R)-Lansoprazole) is the R enantiomer of Lansoprazole, which is a proton pump inhibitor, also binds to NTF2L domain of G3BP1 with Kd of 11 uM, reduces SARS-CoV-2 nucleocapsid protein (N) binds G3BP1 and inhibits viral replication.
PC-25409

Lansoprazole

Proton pump inhibitor

Lansoprazole (AG-1749) is an orally active proton pump inhibitor, inhibits db-cAMP-stimulated acid formation and (H+ + K+)-ATPase with IC50 of 59 nM and 2.1 uM respectively.
PC-24842

Pma1 inhibitor Si01

Pma1 inhibitor

Pma1 inhibitor Si01 is a specific inhibitor of P-type H+-ATPase (proton) Pma1 inhibitor, extends the chronological lifespan (CLS) in fission yeast.
PC-24753

Proton Pump inhibitor 1

Proton pump inhibitor

Proton Pump inhibitor 1 is a potent, selective proton pump inhibitor.
PC-24747

Ilaprazole sodium

Proton pump inhibitor

Ilaprazole sodium (IY-81149) is a potent, orally active proton pump inhibitor that irreversibly inhibits H+/K(+)-ATPase with IC50 of 6 uM.
PC-24746

Esomeprazole

Proton pump inhibitor

Esomeprazole is a proton pump inhibitor that reduces stomach acid secretion by inhibition of the H+/K+-ATPase in the parietal cells.
PC-24092

MFaN

Otop1 modulator

MFaN is a potent and specific positive allosteric modulator (PAM) of proton-gated proton channel Otop1, dose-dependently potentiates mOtop1 currents with EC50 of 10.3 uM (pH 5.5).
PC-23858

ClGBI

Hv1 channel inhibitor

ClGBI is a selective blocker/inhibitor of voltage-gated proton channel Hv1 (HVCN1) with Kd of 26 uM, induces acidification of leukemic Jurkat T cells promoting cell death by apoptosis.

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