Pma1 inhibitor Si01

Chemical Structure : Pma1 inhibitor Si01

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货号: PC-24842Not For Human Use, Lab Use Only.

Pma1 inhibitor Si01 is a specific inhibitor of P-type H+-ATPase (proton) Pma1 inhibitor, extends the chronological lifespan (CLS) in fission yeast.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Pma1 inhibitor Si01 is a specific inhibitor of P-type H+-ATPase (Proton) Pma1 inhibitor, extends the chronological lifespan (CLS) in fission yeast.
Si01 inhibits Pma1 ATPase activity in fission yeast and budding yeast.
Si01 directly inhibits Pma1 of fission yeast which causes the reduction of glucose uptake into the cells.
Si01 reduces the activity of purified Pma1 protein and extends the CLS of not only fission yeast but also budding yeast.

物理化学性质&存储条件

分子量	356.42
分子式	C19H17FN2O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(((2,5-dimethylphenyl)amino)methyl)-5-(2-fluorobenzylidene)thiazolidine-2,4-dione

参考文献

1. Lee AY, et al. Science. 2014 Apr 11;344(6180):208-11.

2. Tamura M, et al. Mol Genet Genomics. 2025 Jun 8;300(1):58.