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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Proton Pump-Ilaprazole sodium
Ilaprazole sodium

Chemical Structure : Ilaprazole sodium

CAS No.: 172152-50-0

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Ilaprazole sodium (IY-81149 sodium)

货号: PC-24747Not For Human Use, Lab Use Only.

Ilaprazole sodium (IY-81149) is a potent, orally active proton pump inhibitor that irreversibly inhibits H+/K(+)-ATPase with IC50 of 6 uM.

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25 mg ￥1280 In stock
50 mg ￥1980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ilaprazole sodium (IY-81149) is a potent, orally active proton pump inhibitor that irreversibly inhibits H+/K(+)-ATPase with IC50 of 6 uM.
Ilaprazole dose-dependently increases gastric pH in anesthetized rats, exhibits superior potency against gastric acid secretion compared with omeprazole.

物理化学性质&存储条件

分子量 388.42
分子式 C19H17N4NaO2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(((4-Methoxy-3-methylpyridin-2-yl)methyl)sulfinyl)-6-(1H-pyrrol-1-yl)-1H-benzo[d]imidazole sodium salt

参考文献

1. Kim EJ, et al. Arzneimittelforschung. 2001 Jan;51(1):51-9.

2. Kwon D, et al. Arzneimittelforschung. 2001;51(3):204-13.

3. Seo KA, et al. Xenobiotica. 2012 Mar;42(3):278-84.

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