| Cat. No. |
Product Name |
Information |
| PC-62040 |
JF-5
PAR1 antagonist
|
JF5 (PAR1 inhibitor JF5) is an allosteric inhibitor of PAR1 that binds to helix 8 of the receptor. |
| PC-61618 |
GB-83
PAR2 inhibitor
|
GB-83 is a selective, reversible PAR2 (Protease-activated receptor 2) antagonist with IC50 of 2 uM. |
| PC-61561 |
ENMD-1068
PAR2 inhibitor
|
ENMD-1068 is a novel selective PAR2 antagonist without inhibitory activity against thrombin-mediated PAR3 and PAR4 signaling. |
| PC-61560 |
ENMD-1068 hydrochloride
PAR2 inhibitor
|
ENMD-1068 is a novel selective PAR2 antagonist without inhibitory activity against thrombin-mediated PAR3 and PAR4 signaling. |
| PC-61308 |
Atopaxar hydrobromide
PAR1 antagonist
|
Atopaxar hydrobromide (E5555) is a potent, reversible protease-activated receptor-1 (PAR-1) antagonist with IC50 of 19 nM. |
| PC-61307 |
Atopaxar
PAR1 antagonist
|
Atopaxar (E5555) is a potent, reversible protease-activated receptor-1 (PAR-1) antagonist with IC50 of 19 nM. |
| PC-61306 |
SCH 79797
PAR1 antagonist
|
SCH79797 is a potent, selective competitive and nonpeptide PAR-1 antagonist with IC50 of 70 nM. |
| PC-61305 |
SCH 79797 dihydrochloride
PAR1 antagonist
|
SCH79797 dihydrochloride is a potent, selective competitive and nonpeptide PAR-1 antagonist with IC50 of 70 nM. |
| PC-61304 |
RWJ-56110
PAR1 antagonist
|
RWJ-56110 is a potent, selective, peptide-mimetic PAR-1 antagonist with binding IC50 of 0.44 uM, with no effect on PAR-2, PAR-3, or PAR-4. |
| PC-60662 |
AC-264613
PAR2 agonist
|
AC-264613 is a novel potent, selective protease-activated receptor PAR2 agonist with potencies ranging from 30-100 nM. |
| PC-60548 |
BMS-986120
PAR4 antagonist
|
BMS-986120 (BMS986120) is a potent, selective, orally bioavailable, and reversible PAR4 antagonist with Kd of 0.098 nM for human PAR4. |
| PC-60321 |
AZ-3451
PAR2 inhibitor
|
AZ-3451 (AZ 3451, AZ3451) is a potent, and selective PAR2 antagonist with Kd of 13.5 nM. |
