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首页-小分子抑制剂&激动剂-GPCR-Protease-activated Receptor (PAR)-ML354
ML354

Chemical Structure : ML354

CAS No.: 89159-60-4

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ML354 (VU0099704)

货号: PC-62125Not For Human Use, Lab Use Only.

ML354 (VU0099704) is a novel potent and selective PAR4 antagonist with IC50 of 140 nM, displays 71-fold selectivity versus PAR-1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    ML354 (VU0099704) is a novel potent and selective PAR4 antagonist with IC50 of 140 nM, displays 71-fold selectivity versus PAR-1。
    ML354 (VU0099704) also displays improved physical properties and is very amenable to future medicinal chemistry development.

    物理化学性质&存储条件

    分子量 282.29
    分子式 C16H14N2O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-methyl-5-nitro-3-phenyl-1H-indole-2-methanol

    参考文献

    1. Wen W, et al. Bioorg Med Chem Lett. 2014 Oct 1;24(19):4708-13.

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