| Cat. No. |
Product Name |
Information |
| PC-24812 |
Ivermectin
CAS 70288-86-7
|
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent, is a specific inhibitor ofimportin α/β-mediated nuclear import with potent antiviral activity towards both HIV-1 and DENV, also is a positive allosteric effector of P2X4 and α7 neuronal nicotinic acetylcholine receptor (nAChRs), also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import. |
| PC-24762 |
Endochin
T. gondii bc1 inhibitor
|
Endochin is an antimalarial agent, inhibits T. gondii growth in vitro (IC50=0.003 nM), inhibits inhibited T.gondii cytochrome c reduction with IC50 of 8.2 nM. |
| PC-24761 |
ELQ-271
T. gondii bc1 inhibitor
|
ELQ-271 is a potent, orally bioavailable inhibitor of T. gondii growth in vitro (IC50=0.1 nM) and is effective against acute and latent toxoplasmosis in mice, inhibits cytochrome c reduction by the T. gondii cytochrome bc(1) complex. |
| PC-24760 |
ELQ-316
T. gondii bc1 inhibitor
|
ELQ-316 is a potent, orally bioavailable inhibitor of T. gondii growth in vitro (IC50=0.007 nM) and is effective against acute and latent toxoplasmosis in mice, inhibits cytochrome c reduction by the T. gondii cytochrome bc(1) complex. |
| PC-24725 |
TAO inhibitor 1
TAO inhibitor
|
TAO inhibitor 1 is a potent, selective trypanosome alternative oxidase (TAO) inhibitor with IC50/Ki of 1.3/3.46 nM (purified TAO), displays broad-spectrum activity against african animal trypanosomes. |
| PC-24700 |
PSAC inhibitor compound 2
PSAC channel inhibitor
|
PSAC inhibitor compound 2 is a small molecule inhibitor of plasmodial surface anion channel (PSAC), targets the PSAC component CLAG3 and inhibits malaria solute transport by PSAC, protects trophozoite-infected RBCs from sorbitol-mediated lysis with pIC50 of 7.9. |
| PC-24699 |
PSAC inhibitor compound 1
PSAC channel inhibitor
|
PSAC inhibitor compound 1 is a small molecule inhibitor of plasmodial surface anion channel (PSAC), targets the PSAC component CLAG3 and inhibits malaria solute transport by PSAC, protects trophozoite-infected RBCs from sorbitol-mediated lysis with pIC50 of 7.3. |
| PC-24372 |
WJM280
Pf cyt b inhibitor
|
WJM280 is a potent, specific inhibitor of P. falciparum mitochondrial protein cytochrome b (Pf cyt b), inhibits LDH activity of P. falciparum 3D7 parasites with EC50 of 40 nM. |
| PC-24371 |
WJM664
PfATP4 inhibitor
|
WJM664 is a small molecule inhibitor of P. falciparum malaria P-type ATPase 4 (PfATP4), inhibits P. falciparum 3D7 parasite growth with EC50 of 13 nM. |
| PC-23936 |
YAT2150
Protein aggregation inhibitor
|
YAT2150 is a potent antileishmanial compound and inhibitor of protein aggregation, exhibits potent antiplasmodial activity with IC50 of 90 nM. |
| PC-23895 |
MMV019918
Anti-malaria
|
MMV019918 is a specific small molecule inhibitor of trypanocidal cysteine protease, acts directly against the trypomastigote and the intracellular amastigote forms of T. cruzi at 3 μM. |
| PC-23894 |
MMV019017
Anti-malaria
|
MMV019017 is a small molecule anti-malaria compound, maybe inhibit PfATP4, an ATPase transporter located on the plasma membrane of the malaria parasite. |
