Chemical Structure : WHZ-13
货号: PC-27570Not For Human Use, Lab Use Only.
WHZ-13 is a potent, selective P. falciparum 20S proteasome (Pf20S) inhibitor with IC50 of 4.1 nM for Pf20S β5, has 91-fold and 24-fold selectivity over β5c and β5i, shows antimalarial EC50 of 3.1 nM against Pf 3D7.
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WHZ-13 is a potent, selective P. falciparum 20S proteasome (Pf20S) inhibitor with IC50 of 4.1 nM for Pf20S β5, has 91-fold and 24-fold selectivity over β5c and β5i, shows antimalarial EC50 of 3.1 nM against Pf 3D7.
| 分子量 | 512.63 | |
| 分子式 | C26H32N4O5S | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
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1. Wenhu Zhan, et al. J Med Chem. 2019 Jul 11;62(13):6137-6145.
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