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BKI-1

Chemical Structure : BKI-1

CAS No.: 1320266-08-7

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BKI-1 (Bumped Kinase Inhibitor-1)

货号: PC-27936Not For Human Use, Lab Use Only.

BKI-1 (Bumped Kinase Inhibitor-1) is a highly potent bumped kinase inhibitor with IC50 of 4 nM for WT rPfCDPK4, potently inhibits the exflagellation of P. falciparum, does not block the proliferation of asexual parasites.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BKI-1 (Bumped Kinase Inhibitor-1) is a highly potent bumped kinase inhibitor with IC50 of 4 nM for WT rPfCDPK4, potently inhibits the exflagellation of P. falciparum, does not block the proliferation of asexual parasites.

物理化学性质&存储条件

分子量 402.50
分子式 C23H26N6O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(6-ethoxynaphthalen-2-yl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

参考文献

1. Ojo KK, et al. J Clin Invest. 2012 Jun;122(6):2301-5.

2. Oduselu GO, et al. Bioinform Biol Insights. 2026 Aug 28;20:11779322261483607.

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