| Cat. No. |
Product Name |
Information |
| PC-45121 |
WY-14643
PPARα agonist
|
WY-14643 (Pirinixic acid) is a potent, selective PPARα agonist with EC50 of 0.63 uM. |
| PC-42713 |
GW 501516
PPARδ agonist
|
GW 501516 (GW516) is a potent and subtype-selective PPARδ agonist with Ki of 1.1 nM in human PPARδ binding assay. |
| PC-45209 |
Rosiglitazone
PPARγ agonist
|
Rosiglitazone (BRL49653) is a potent and selective PPARγ agonist that binds to the PPARγ ligand-binding domain with a Kd of 40 nM. |
| PC-42693 |
BMS-687453
PPARα agonist
|
BMS-687453 (BMS687453) is a potent and selective PPARα agonist with EC50 of 10 nM for human PPARα and 410-fold selectivity over human PPARγ in PPAR-GAL4 transactivation assays. |
| PC-44041 |
Aleglitazar
PPARα/γ agonist
|
Aleglitazar (R1439, RO 0728804) is a potent and balanced dual PPARα/γ agonist (EC50= 50/21 nM). |
| PC-45753 |
Saroglitazar magnesium salt
PPAR agonist
|
Saroglitazar magnesium salt is a small molecule PPAR agonist with predominant PPARα and moderate PPARγ activity with EC50 of 0.65 pM and 3 nM respectively. |
| PC-45752 |
Saroglitazar
PPARα agonist
|
Saroglitazar is a PPAR agonist with predominant PPARα and moderate PPARγ activity with EC50 of 0.65 pM and 3 nM respectively. |
| PC-45067 |
Elafibranor
PPARα/δ agonist
|
Elafibranor (GFT505) is a potent dual PPAR α/δ agonist with EC50 of 45 and 175 nM, respectively. |
| PC-45390 |
Pemafibrate
PPARα agonist
|
Pemafibrate (K-877) is a highly potent, specific PPARα agonist with EC50 of 1 nM. |
| PC-24240 |
Glabridin
PPARγ agonist
|
Glabridin is a natural isoflavan from Glycyrrhiza glabra L., binds to and activates PPARγ with EC50 of 6.1 uM, inhibits NADPH oxidase-induced cell-mediated oxidation, exhibits antioxidant, anti-bacterial, antitumor and anti-inflammatory activities. |
| PC-24111 |
TPST-1120
PPARα inhibitor
|
Amezalpat (TPST-1120, TPST1120) is potent, selective and orally bioavailable inhibitor of peroxisome proliferator-activated receptor α (PPARα) with IC50 of 0.04 uM (human PPARα), >250-fold selectivity over the other PPAR isoforms (PPAR β/δ and γ). |
| PC-24032 |
PPARα agonist A190
PPARδ agonist
|
PPARα agonist A190 is a highly selective and potent nonfibrate PPARα agonist with EC50 of 37 nM (hPPARα), exhibits >2,700-fold selectivity for PPARα over other PPAR isoforms. |
