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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-PPAR-Aleglitazar
Aleglitazar

Chemical Structure : Aleglitazar

CAS No.: 475479-34-6

Aleglitazar (R1439;RO0728804;R-1439;RO-0728804;R 1439;RO 0728804)

货号: PC-44041Not For Human Use, Lab Use Only.

Aleglitazar (R1439, RO 0728804) is a potent and balanced dual PPARα/γ agonist (EC50= 50/21 nM).

规格 价格 库存 数量
10 mg Get quote
25 mg Get quote
50 mg Get quote
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Aleglitazar (R1439, RO 0728804) is a potent and balanced dual PPARα/γ agonist (EC50= 50/21 nM).
Aleglitazar (R1439, RO 0728804) shows high efficacy in animal models of type II diabetes.

物理化学性质&存储条件

分子量 437.5081
分子式 C24H23NO5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αS)-

参考文献

1. Bénardeau A, et al. Bioorg Med Chem Lett. 2009 May 1;19(9):2468-73.

2. Qian J, et al. Cardiovasc Drugs Ther. 2016 Apr;30(2):129-41.

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