Fenofibrate

Chemical Structure : Fenofibrate

CAS No.: 49562-28-9

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货号: PC-45176Not For Human Use, Lab Use Only.

Fenofibrate is a PPARα agonist that exhibits EC50 of 18 and 30 uM for murine and human PPARα, respectively, in a transactivation assay.

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生物&药学活性

Fenofibrate is a PPARα agonist that exhibits EC50 of 18 and 30 uM for murine and human PPARα, respectively, in a transactivation assay.
Fenofibrate reduces both LDL and VLDL levels, as well as increasing HDL levels and reduces triglyceride levels.
Fenofibrate mainly used to reduce cholesterol levels in people at risk of cardiovascular disease.

物理化学性质&存储条件

分子量	360.8313
分子式	C20H21ClO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 47 mg/mL
Chemical Name/SMILES	Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester

参考文献

1. Vu-Dac N, et al. J Biol Chem. 1998 Oct 2;273(40):25713-20.

2. Gebel T, et al. FEBS Lett. 1992 Aug 31;309(1):37-40.

3. Willson TM, et al. J Med Chem. 2000 Feb 24;43(4):527-50.

Fenofibrate

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Fenofibrate

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