| Cat. No. |
Product Name |
Information |
| PC-22519 |
Escitalopram
SERT inhibitor
|
Escitalopram ((S)-Citalopram) is a potent, selective serotonin reuptake inhibitor with Ki of 0.89 nM (SERT), shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). |
| PC-22426 |
SRI-30827
DAT modualtor
|
SRI-30827 is a selective, allosteric modulator of dopamine transporter (DAT), inhibits DA uptake in rat synaptosomes with IC50 of 0.5 nM, counteracts Tat-induced potentiation of cocaine reward. |
| PC-22149 |
IP2015 hydrochloride
Monoamine reuptake inhibitor
|
IP2015 (IPED2015, Pudafensine, NS18313) hydrochloride is a novel monoamine transport inhibitor with IC50 of 9.5, 72.0 and 3.8 nM for hSET, hNAT and hDAT respectively, inhibits dopamine uptake and binds to DAT. |
| PC-22148 |
IP2015
Monoamine reuptake inhibitor
|
IP2015 (IPED2015, Pudafensine, NS18313) is a novel monoamine transport inhibitor with IC50 of 9.5, 72.0 and 3.8 nM for hSET, hNAT and hDAT respectively, inhibits dopamine uptake and binds to DAT. |
| PC-22086 |
JPC-141 hydrochloride
VMAT2 inhibitor
|
JPC-141 hydrochloride is a potent, selective vesicular monoamine transporter-2 (VMAT2) inhibitor, potently inhibits [3H]dopamine uptake by VMAT2 in striatal vesicles with Ki of 52 nM. |
| PC-22085 |
JPC-141
VMAT2 inhibitor
|
JPC-141 is a potent, selective vesicular monoamine transporter-2 (VMAT2) inhibitor, potently inhibits [3H]dopamine uptake by VMAT2 in striatal vesicles with Ki of 52 nM. |
| PC-21534 |
(S)-CE-123
DAT inhibitor
|
(S)-CE-123 is a specific small molecule dopamine transporter (DAT) inhibitor, improves memory acquisition and memory retrieval. |
| PC-21233 |
CDTP-32476
Dopamine reuptake inhibitor
|
CDTP-32476 is a potent slow-onset dopamine reuptake blocker with an affinity of 8.6 nM, CDTP-32476 is moderately selective (14-fold) versus NE reuptake blockade with little effect on the SERT. |
| PC-21114 |
D-578
Monoamine reuptake inhibitor
|
D-578 is a potent, orally active triple monoamine reuptake inhibitor with Ki values of 16.2. 16.2, 3.23 nM, and 29.6, 20.6, 6.10 nM for the rat brain and cloned human dopamine, serotonin and norepinephrine transporters, respectively. |
| PC-20766 |
ZINC000443438219
SERT inhibitor
|
ZINC000443438219 (Compound 8219) is a highly potent, selective and non-competitive inhibitor of serotonin transporter (SERT) with Ki of 3 nM. |
| PC-20765 |
ZINC000006658090
SERT inhibitor
|
ZINC000006658090 (Compound 8090) is a highly potent, selective and non-competitive inhibitor of serotonin transporter (SERT) with Ki of 14 nM. |
| PC-20763 |
Lu AF60097
SERT inhibitor
|
Lu AF60097 is a high affinity, allosteric inhibitor of serotonin transporter (SERT) inhibitor with IC50 of 31 nM for inhibition of [3H]IMI dissociation, targets the extracellular vestibule (S2 site). |
