| Cat. No. |
Product Name |
Information |
| PC-62373 |
FFN-206 dihydrochloride
VMAT2 inhibitor
|
FFN-206 is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles. |
| PC-61998 |
Edivoxetine hydrochloride
Norepinephrine reuptake inhibitor
|
Edivoxetine (LY2216684) is a novel potent, selective norepinephrine reuptake inhibitor (NERI) being evaluated as adjunctive treatment for major depressive disorder (MDD). |
| PC-61997 |
Edivoxetine
Norepinephrine reuptake inhibitor
|
Edivoxetine (LY2216684) is a novel potent, selective norepinephrine reuptake inhibitor (NERI) being evaluated as adjunctive treatment for major depressive disorder (MDD).. |
| PC-61884 |
PF-184298
Monoamine reuptake inhibitor
|
PF-184298 is a potent, selective dual serotonin and noradrenaline monoamine reuptake inhibitor (SNRI) with IC50 of 6 nM and 21 nM, respectively. |
| PC-70169 |
Amitifadine
Monoamine reuptake inhibitor
|
Amitifadine (DOV-21947, EB-1010) is a triple monoamine reuptake inhibitor, inhibits the reuptake of 5-HT, norepinephrine and dopamine in HEK 293 cells with IC50 of 12, 23 and 96 nM, respectively. |
| PC-60053 |
Solriamfetol hydrochloride
|
Solriamfetol hydrochloride (JZP-110, R-228060, ADX-N05, YKP-10A) is a norepinephrine-dopamine reuptake inhibitor that inhibits dopamine and norepinephrine transporter with IC50 of 2.9 and 4.4 uM, respectively. |
| PC-46649 |
Paroxetine hydrochloride
|
Paroxetine hydrochloride (BRL29060 hydrochloride) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
| PC-45454 |
Amitifadine hydrochloride
|
Amitifadine hydrochloride (DOV-21947 hydrochloride) is a triple monoamine reuptake inhibitor that inhibits the reuptake of [3H]serotonin, [3H]norepinephrine, and [3H]dopamine in HEK 293 cells expressing the corresponding human recombinant transporters (IC50 values of 12, 23, and 96 nM, respectively). |
| PC-45076 |
Valbenazine
VMAT2 inhibitor
|
Valbenazine (NBI-98854) is a highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor with Ki of 110-190 nM. |
| PC-23147 |
Citalopram
SSRI
|
Citalopram is an orally active selective serotonin reuptake inhibitor (SSRI), shows antidepressant and enhances serotoninergic neurotransmission. |
| PC-22974 |
MRS7232
DAT inhibitor
|
MRS7232 is an allosteric, non-competitive inhibitor of human dopamine transporter (DAT) with EC50 of 34 nM, and norepinephrine transporter (NET), also is a potent A3AR agonist with Ki of 14.5 nM. |
| PC-22973 |
MRS7292
DAT inhibitor
|
MRS7292 is an allosteric, non-competitive inhibitor of human dopamine transporter (DAT) with EC50 of 35 nM, and norepinephrine transporter (NET), also is a potent A3AR agonist with Ki of 5.38 nM. |
