Ampreloxetine (TD-9855) | Monoamine reuptake inhibitor

Chemical Structure : Ampreloxetine

CAS No.: 1227056-84-9

加入收藏

Ampreloxetine (TD-9855, TD9855)

货号: PC-35438Not For Human Use, Lab Use Only.

Ampreloxetine (TD-9855) is a potent monoamine reuptake inhibitor with pIC50 of 8.0, 8.6 and 6.8 for human NET, SERT, and DAT, respectively.

规格	价格	库存
5 mg	￥2180	In stock
10 mg	￥3480	In stock
25 mg	￥5580	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Ampreloxetine (TD-9855) is a potent monoamine reuptake inhibitor with pIC50 of 8.0, 8.6 and 6.8 for human NET, SERT, and DAT, respectively.
Ampreloxetine displays an inhibitory selectivity of 4- to 10-fold for NE at human and rat transporter.
Ampreloxetine engaged norepinephrine transporters (NET) and serotonin transporters (SERT) in rat spinal cord, with a plasma EC50 of 11.7 ng/mL and 50.8 ng/mL, respectively.
TD-9855 is an investigational dual norepinephrine (NE) and serotonin (5-HT) reuptake inhibitor with selectivity for NE over 5-HT (NSRI).

物理化学性质&存储条件

分子量	321.343
分子式	C18H18F3NO
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-{2-[(2,4,6-trifluorophenoxy)methyl]phenyl}piperidine

参考文献

1. Smith JA, et al. Int J Neuropsychopharmacol. 2014 Dec 13;18(2). pii: pyu027.

Ampreloxetine (TD-9855, TD9855)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Ampreloxetine (TD-9855, TD9855)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.