Atomoxetine ((R)-Tomoxetine, LY-139603)

Chemical Structure : Atomoxetine

CAS No.: 83015-26-3

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货号: PC-63052Not For Human Use, Lab Use Only.

Atomoxetine ((R)-Tomoxetine, LY-139603) is a potent, selective norepinephrine (NE) transporter inhibitor with Ki of 5 nM.

规格	价格	库存
100 mg	￥580	In stock
500 mg	￥1280	In stock
1 g		Get quote

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生物&药学活性

Atomoxetine ((R)-Tomoxetine, LY-139603) is a potent, selective norepinephrine (NE) transporter inhibitor with Ki of 5 nM.
Atomoxetine shows weak affinity for 5-HT and dopamine transporters with IC50 of 77 and 1,451 nM, respectively.
Atomoxetine has been approved for the treatment of attention deficit hyperactivity disorder (ADHD).

物理化学性质&存储条件

分子量	255.361
分子式	C17H21NO
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3R)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine

参考文献

1. Bymaster FP, et al. Neuropsychopharmacology. 2002 Nov;27(5):699-711.

2. Sauer JM, et al. Clin Pharmacokinet. 2005;44(6):571-90.

3. Passamonti L, et al. Psychopharmacology (Berl). 2017 Aug;234(15):2289-2297.