FFN-206 dihydrochloride | VMAT2 inhibitor | Probechem Biochemicals

Chemical Structure : FFN-206 dihydrochloride

CAS No.: 1883548-88-6

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FFN-206 dihydrochloride (FFN206)

货号: PC-62373Not For Human Use, Lab Use Only.

FFN-206 is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles.

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5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3480	In stock
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生物&药学活性

FFN-206 dihydrochloride is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles.
The apparent Km of FFN206 at VMAT2 was found to be 1.16±0.10 uM, similar to that of dopamine.
FFN-206 is an useful tool for optical examination of VMAT2 function in cell culture.

物理化学性质&存储条件

分子量	291.172
分子式	C12H16Cl2N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(2-Aminoethyl)-7-(methylamino)-2H-1-benzopyran-2-one dihydrochloride

参考文献

1. Hu G, et al. ACS Chem Biol. 2013 Sep 20;8(9):1947-54.

FFN-206 dihydrochloride (FFN206)

生物&药学活性

物理化学性质&存储条件

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FFN-206 dihydrochloride (FFN206)

生物&药学活性

物理化学性质&存储条件

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