| Cat. No. |
Product Name |
Information |
| PC-42604 |
Daclatasvir
HCV NS5A inhibitor
|
Daclatasvir (BMS-790052) is a potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons. |
| PC-42603 |
Daclatasvir dihydrochloride
HCV NS5A inhibitor
|
Daclatasvir (BMS-790052) dihydrochloride is a potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons. |
| PC-45961 |
Lomibuvir
HCV NS5B inhibitor
|
Lomibuvir (VX-222, VCH-222) is a potent and selective, nonnucleoside inhibitor of HCV NS5B polymerase inhibitor with Kd of 17 nM. |
| PC-42605 |
NM107
HCV NS5B inhibitor
|
NM107 (Valopicitabine) is a nucleoside inhibitor of HCV NS5B polymerase with EC50 of 1.23 uM against HCV 1b replicon cells. |
| PC-42023 |
Peretinoin
|
Peretinoin (NIK333) is an orally available, synthetic retinoid with potential antineoplastic and chemopreventive activities. |
| PC-42646 |
Tegobuvir
HCV NS5B inhibitor
|
Tegobuvir (GS-333126, GS-9190) is a nonnucleoside inhibitor of HCV NS5B polymerase that acts as a potent inhibitor of HCV genotype 1. |
| PC-22913 |
Coblopasvir dihydrochloride
HCV NS5A inhibitor
|
Coblopasvir (KW136, KW-136) dihydrochloride is a novel HCV NS5A inhibitor under development for treatment of HCV infection. |
| PC-22912 |
Bemnifosbuvir
HCV inhibitor
|
Bemnifosbuvir (AT-527, RG-6422) is a novel phosphoramidate prodrug of AT-511 that has potent in vitro activity against HCV (EC50=5-28 nM), also inhibits replication of SARS-CoV-2 with EC90 of 0.47 uM. |
| PC-21356 |
Sofosbuvir
HCV NS5B inhibitor
|
Sofosbuvir (GS-7977, PSI-7977) is a prodrug of 2'-F-2'-C-methyluridine monophosphate and HCV NS5B polymerase inhibitor, is active against GT 1a, 1b, and 2a (strain JFH-1) replicons and chimeric replicons containing GT 2a (strain J6), 2b, and 3a NS5B polymerase. |
| PC-21355 |
Dasabuvir
HCV NS5B inhibitor
|
Dasabuvir (ABT-333) is a potent, selective, and nonnucleoside inhibitor of HCV NS5B polymerase with IC50 of 2.2-10.7 nM for HCV genotype 1a and 1b. |
| PC-21354 |
Ledipasvir
HCV NS5A inhibitor
|
Ledipasvir (GS-5885) is a potent, selective and oral HCV NS5A inhibitor with EC50 of 31 pM and 4 pM against GT1a and GT1b, respectively. |
| PC-21353 |
Elbasvir
HCV NS5A inhibitor
|
Elbasvir (MK-8742) is a potent, tetracyclic indole-based HCV NS5A inhibitor, shows broad HCV genotype activity with IC50 of 0.003, 0.003, 0.004, 0.5, 2.4 nM for genotype 1b, 2a, 1a, 1aL31V and 1aY93H, respectively. |
