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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HCV-Daclatasvir dihydrochloride
Daclatasvir dihydrochloride

Chemical Structure : Daclatasvir dihydrochloride

CAS No.: 1009119-65-6

Daclatasvir dihydrochloride (BMS-790052 dihydrochloride, BMS790052 dihydrochloride)

货号: PC-42603Not For Human Use, Lab Use Only.

Daclatasvir (BMS-790052) dihydrochloride is a potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons.

规格 价格 库存 数量
50 mg ¥1280 In stock
100 mg ¥1980 In stock
250 mg Get quote
1 g Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Daclatasvir (BMS-790052) dihydrochloride is a potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons.
Daclatasvir exhibits picomolar EC(50) towards replicons expressing a broad range of HCV genotypes and the JFH-1 genotype 2a infectious virus in cell culture.

物理化学性质&存储条件

分子量 811.7969
分子式 C40H52Cl2N8O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 56 mg/mL

Chemical Name/SMILES

Carbamic acid, N,N'-[[1,1'-biphenyl]-4,4'-diylbis[1H-imidazole-5,2-diyl-(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]bis-, C,C'-dimethyl ester, hydrochloride (1:2)

参考文献

1. Gao M, et al. Nature. 2010 May 6;465(7294):96-100.

2. Lemm JA, et al. Antimicrob Agents Chemother. 2011 Aug;55(8):3795-802.

3. Fridell RA, et al. Antimicrob Agents Chemother. 2010 Sep;54(9):3641-50.

4. Fridell RA, et al. J Virol. 2011 Jul;85(14):7312-20.

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