| Cat. No. |
Product Name |
Information |
| PC-21528 |
GB1490
Galectin-1 inhibitor
|
GB1490 is a potent, selective and orally available galectin-1 (gal-1) inhibitor with Kd value of 0.4 uM and 0.23 uM for human and mouse galectin-1, respectively. |
| PC-49544 |
GB1211
Galectin-3 inhibitor
|
Selvigaltin (GB1211) is a highly potent, selective and orally active Galectin-3 inhibitor with binding Kd of 25 nM in FP assays. |
| PC-36033 |
GB1107
Galectin-3 inhibitor
|
GB1107 (GB-1107, GB 1107) is a potent, selective, orally active inhibitor of Galectin-3 (Gal-3) with Kd of 37 nM (human Galectin-3). |
| PC-63369 |
LLS30
Galectin-1 inhibitor
|
LLS30 is a potent, allosteric Galectin-1 (Gal-1) inhibitor, inhibits AR negative cells PC3, DU145, and AR positive cells, 22RV1 and CWR-R1 cells with IC50 of 10.4 μM, 5.3 μM, 3.3 μM and 5.9 μM, respectively. |
| PC-61647 |
LLS2
Galectin-1 inhibitor
|
LLS2 is a novel potent Galectin-1 (Gal1) inhibitor that decreases membrane-associated H-Ras and K-Ras and contributed to the suppression of pErk pathway. |
| PC-61646 |
OTX008
Galectin-1 inhibitor
|
OTX008 (Calixarene 0118, PTX-008) is a is a calixarene derivative designed to bind the Galectin-1 (Gal1) amphipathic β-sheet conformation. |
| PC-45754 |
TD139
Galectin-3 inhibitor
|
TD139 (GB0139, Olitigaltin) is a highly potent, selecitve inhibitor of Galectin-3 (Gal-3) carbohydrate binding domain with Ki of 14 nM. |
| PC-23627 |
GB2095
Galectin-3 inhibitor
|
GB2095 is a highly potent, selective and in vivo active galectin-3 (Gal-3) inhibitor with Kd of 36 nM (human Gal-3), 14-fold selectivity for galectin-3 over all other galectins. |
| PC-22405 |
GB1908
Galectin-1 inhibitor
|
GB1908 is a potent, selective and orally available galectin-1 (Gal-1) inhibitor with Kd of 57 nM and 72 nM for human and mouse Gal-1 respectively in fluorescence polarization assays. |
