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首页-小分子抑制剂&激动剂-GPCR-CGRP Receptor

Request The Product List ofCGRP Receptor CGRP Receptor

Cat. No. Product Name Information
PC-38690

Zavegepant

CGRP antagonist

Zavegepant (Vazegepant, BHV-3500, BMS-742413) is a high affinity, selective antagonist of calcitonin gene-related peptide (CGRP) receptor (hCGRP, Ki=0.023 nM), has demonstrated efficacy in the acute treatment of migraine.
PC-72952

BMS-846372

CGRP antagonist

BMS-846372 (BMS846372) is a potent, selective, orally active CGRP receptor antagonist with Ki of 0.07 nM (hCGRP).
PC-72787

FE 205030

CGRP antagonist

FE 205030 (FE205030) is a potent, selective peptidic CGRP antagonist with IC50 of 0.2 nM.
PC-35253

Ubrogepant

CGRP inhibitor

Ubrogepant (MK-1602) is a novel potent, selective, oral calcitonin gene-related peptide receptor (CGRP) antagonist for acute treatment of migraine..
PC-62994

MK-8825

CGRP inhibitor

MK-8825 is a highly potent, selective, orally bioavailable CGRP receptor antagonist with Ki of 17 nM for rat CGRP.
PC-60031

Atogepant

CGRP inhibitor

Atogepant (MK-8031) is a potent and selective calcitonin gene-related peptide (CGRP) receptor antagonist with Ki of 2 pM (hCGRP).
PC-42296

Olcegepant hydrochloride

CGRP inhibitor

Olcegepant hydrochloride (BIBN4096BS) is the first small molecule selective calcitonin gene-related peptide (CGRP) receptor antagonist with Ki of 14.4 nM for hCGRP.
PC-42294

Olcegepant

CGRP antagonist

Olcegepant (BIBN-4096, BIBN4096BS) is the first small molecule selective calcitonin gene-related peptide (CGRP) receptor antagonist with Ki of 14.4 nM for hCGRP.
PC-45811

MK-0974

CGRP inhibitor

Telcagepant (MK-0974) is a potent, selective, orally bioavailable CGRP receptor antagonist with Ki of 0.77 nM.
PC-42516

MK-3207

CGRP inhibitor

MK-3207 is a highly potent, selective CGRP receptor antagonist with Ki of 21 pM in in vitro binding assay and IC50 of 0.12 nM in cell-based functional assay.
PC-21792

Rimegepant

CGRP inhibitor

Rimegepant (BMS-927711) is a potent, selective and orally active calcitonin gene-related peptide (CGRP) antagonist with Ki of 0.027 nM, inhibits CGRP-stimulated cAMP production in SK-N-MC cells with EC50 of 0.14 nM.
PC-21156

BMS-694153

CGRP antagonist

BMS-694153 is a potent, selective calcitonin gene-related peptide (CGRP) receptor antagonist with Ki of 0.013 nM for hCGRP (inhibition of 125I-CGRP binding in SK-N-MC cell membranes).

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