| Cat. No. |
Product Name |
Information |
| PC-24373 |
VCP746
A1AR agonist
|
VCP746 is a selective, hybrid molecule A1 adenosine receptor (A1AR) biased agonist with Ki of 60 nM, and pEC50 of 9.05 in FlpIn-CHO cells stably expressing the A1AR. |
| PC-24291 |
HZ-086
A2AR inhibitor
|
HZ-086 is a potent and selective inhibitor of adenosine A2A receptor (A2AR) with Ki of 1.4 nM (hA2A), >250-fold selective over A1R and A3R. |
| PC-24196 |
Zaladenant
A2a receptor inhibitor
|
Zaladenant is a potent, selective adenosine A2a receptor inhibitor with IC50 of 0.23 nM. |
| PC-23655 |
Regadenoson
A2A receptor antagonist
|
Regadenoson (CVT-3146) is a potent, selective A2A adenosine receptor agonist, and short-acting coronary vasodilator. |
| PC-23365 |
TC-G 1004
A2A receptor antagonist
|
TC-G 1004 is a potent, selective orally active A2A adenosine receptor (A2A R) antagonist, with Ki values of 0.44 nM and 80 nM for hA2A and hA1, respectively. |
| PC-22838 |
AR-001
Adenosine A1 receptor agonist
|
AR-001 is a selective adenosine A1 receptor agonist with EC50 of 9.35 uM in HEK293-aeqα15/ADORA1 cells, increases adenosine A1 receptor expression and mRNA level in the hypothalamus of mice, exhibits hypnotic efficacy. |
| PC-22753 |
MRS-1706
A2BR antagonist
|
MRS-1706 (MRS1706) is a potent and selective adenosine A2B receptor (A2BR) inverse agonist / antagonist with Ki of 1.39 nM, >100-fold selective over A2A, A1 and A3 receptors. |
| PC-22361 |
LUF5834
A2AR agonist
|
LUF5834 is a potent, selective, non-adenosine adenosine A1 receptor adenosine receptor (A2BR) partial agonist with EC50 of 12 nM (hA2B), 45-fold selective over hA3, also shows high affinity with Ki of 2.6 nM and 28 nM for hA1 and hA2A, respectively. |
| PC-22194 |
CF102
A3AR agonist
|
Namodenoson (2-Cl-IB-MECA, CF-102) is a potent, selective A3 adenosine receptor (A3AR) agonist with Ki of 0.33 nM, displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively. |
| PC-22012 |
CVT-7124
A2B adenosine receptor inhibitor
|
CVT-7124 (CVT7124) is a highly potent, selective A2B adenosine receptor antagonist with Ki of 6 nM (hA2B), >830-fold selective over A1, A2A and A3 receptors. |
| PC-21511 |
MRS7469
A1AR agonist
|
MRS7469 is a potent and selective orthosteric A1 adenosine receptor (A1AR) agonist with Ki of 2.14 nM, >2000-fold selective for A1AR over other adenosine receptors. |
| PC-20644 |
VUF-5574
A3 adenosine antagonist
|
VUF-5574 (VUF5574) is a potent, selective A3 adenosine receptor antagonist with high affinity (Ki=4.03 nM, human A3 receptor). |
