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首页-小分子抑制剂&激动剂-GPCR-Adenosine Receptor-MIPS2712
MIPS2712

Chemical Structure : MIPS2712

CAS No.: 2101814-45-1

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MIPS2712

货号: PC-25475Not For Human Use, Lab Use Only.

MIPS2712 is a potent, selective, covalent, irreversible antagonist of A1 adenosine receptor (A1AR)with pKB value of 8.0, >100-fold selective for the A1AR over the A2AAR.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MIPS2712 is a potent, selective, covalent, irreversible antagonist of A1 adenosine receptor (A1AR)with pKB value of 8.0, >100-fold selective for the A1AR over the A2AAR.

物理化学性质&存储条件

分子量 517.60
分子式 C24H31N5O6S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-((3-(8-cyclohexyl-2,6-dioxo-1-propyl-1,2,6,7-tetrahydro-3H-purin-3-yl)propyl)carbamoyl)benzenesulfonic acid

参考文献

1. Glukhova A, et al. Cell. 2017 Feb 23;168(5):867-877.e13.

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