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首页-小分子抑制剂&激动剂-GPCR-Adenosine Receptor-A2AR antagonist P400
A2AR antagonist P400

Chemical Structure : A2AR antagonist P400

CAS No.: 2042564-03-2

A2AR antagonist P400

货号: PC-26044Not For Human Use, Lab Use Only.

A2AR antagonist P400 is a highly potent, selective adenosine A2A receptor (A2AR) antagonist with Ki of 5.3 fM (human cloned A2AR), ameliorates EAE symptoms by attenuating neuroinflammation and demyelination.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

A2AR antagonist P400 is a highly potent, selective adenosine A2A receptor (A2AR) antagonist with Ki of 5.3 fM (human cloned A2AR), ameliorates EAE symptoms by attenuating neuroinflammation and demyelination.

物理化学性质&存储条件

分子量 353.40
分子式 C17H15N5O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(furan-2-yl)-N5-(3-methoxybenzyl)thiazolo[5,4-d]pyrimidine-5,7-diamine

参考文献

1. M Morozzi, et al. Neuropharmacology. 2026 May 1:288:110857.

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