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首页-小分子抑制剂&激动剂-GPCR-Adenosine Receptor-A2AR antagonist P625
A2AR antagonist P625

Chemical Structure : A2AR antagonist P625

CAS No.: 2561434-42-0

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A2AR antagonist P625

货号: PC-26045Not For Human Use, Lab Use Only.

A2AR antagonist P625 is a highly potent, selective adenosine A2A receptor (A2AR) antagonist with Ki of 15.1 nM (human cloned A2AR), ameliorates EAE symptoms by attenuating neuroinflammation and demyelination.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

A2AR antagonist P625 is a highly potent, selective adenosine A2A receptor (A2AR) antagonist with Ki of 15.1 nM (human cloned A2AR), ameliorates EAE symptoms by attenuating neuroinflammation and demyelination.

物理化学性质&存储条件

分子量 399.52
分子式 C19H25N7OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(furan-2-yl)-5-(4-(2-(pyrrolidin-1-yl)ethyl)piperazin-1-yl)thiazolo[5,4-d]pyrimidin-7-amine

参考文献

1. M Morozzi, et al. Neuropharmacology. 2026 May 1:288:110857.

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