nAChR (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-61621	ABT-107	ABT-107 is a potent and selective α7 nAChR agonist with Ki of 0.2-0.6 nM for rat or human cortex α7 nAChRs.
PC-61591	BMS-933043	BMS-933043 is a novel highly selective, potent α7 nAChR partial agonist with binding Ki of 3.3 and 8.1 nM for rat and human α7, respectively.
PC-60819	NS3861	A potent, subtype-selective α3β4 nAChR partial agonist with Ki of 0.62 nM.
PC-60794	RO 5126946	A novel potent, selective, orally bioavailable and brain-penetran α7nAChR positive allosteric modulator with EC50 of 60 nM.
PC-60678	KAB-18	A potent, selective, noncompetitive human α4β2 nAChRs negative allosteric modulator with IC50 of 13.5 uM, displays no inhibitory activity on Hα3β4 nAChRs at 100 uM..
PC-70038	MG-624	A selective antagonist of α7 nAChR that inhibits α-Bgtx binding to α7 with Ki of 106 nM.
PC-45968	Galanthamine	A potent allosteric potentiating ligand of human nAChRs α4β2, α3β4, and α6β4.

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