| Cat. No. |
Product Name |
Information |
| PC-22739 |
Mifepristone
Progesterone receptor antagonist
|
Mifepristone (RU-486, RU486) is a potent, selective progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50 of 0.2 nM and 2.6 nM respectively. |
| PC-38286 |
CPAG-1
PGRMC2 activator
|
CPAG-1 (PGRMC2 activator CPAG-1) is a small-molecule activator of PGRMC2. |
| PC-63436 |
Vilaprisan
Progesterone receptor modulator
|
Vilaprisan (BAY 1002670) is a highly potent and selective progesterone receptor (PR) modulator (SPRM). |
| PC-43374 |
Nestorone
PR agonist
|
Nestoron2 (ST1435, Elcometrine) is a 19-norprogesterone derivative and steroidal progestin which is used as a hormonal contraceptive, a high-affinity agonist of the progesterone receptor. |
| PC-43085 |
Desogestrel
Progesterone receptor agonist
|
Desogestrel (Org-2969) is a third-generation 19-nortestosterone derivative progestogen and agonist of the progesterone receptor. |
| PC-42366 |
Gestrinone
Progesterone receptor antagonist
|
Gestrinone (R-2323) is a synthetic steroid that is used in the treatment of endometriosis, has mixed progestogenic and antiprogestogenic, weak androgenic, antigonadotropic, and functional antiestrogen activity.. |
| PC-62694 |
PGRMC2 activator 25
PGRMC2 activator
|
PGRMC2 activator 25 gain-of-function ligand for PGRMC2 (progesterone receptor membrane component 2) to promote adipogenesis. |
| PC-61896 |
PF-02413873
PR antagonist
|
PF-02413873 (PF-2413873) is a potent, selective, fully competitive, and orally active progesterone receptor (PR) antagonist with Ki of 9.7 nM. |
| PC-70186 |
AG-205
PGRMC1 inhibitor
|
AG-205 is a small molecule inhibitor of progesterone receptor membrane component 1 (PGRMC1) that alters the spectroscopic properties of the PGRMC1-heme complex. |
| PC-60075 |
Onapristone
Progesterone receptor antagonist
|
Onapristone (ZK-89299, ZK-299) is a synthetic, steroidal progesterone receptor (PR) antagonist with reduced antiglucocorticoid activity compared to mifepristone. |
| PC-27696 |
Nestorone
PR agonist
|
Nestorone (ST-1435) is a potent nonandrogenic progestin and selective progesterone receptor (PR) agonist, displays greater potency than progesterone to transactivate the human PR, has shown neuroprotective potential, also exhibits anti-inflammatory activity. |
| PC-27686 |
Tanaproget
PR agonist
|
Tanaproget (NSP-989, WAY-166989) is a potent and selective, nonsteroidal progesterone receptor (PR) agonist with EC50 of 0.15 nM, displaces [3H]R5020 (synthetic steroidal progestin) binding to the human PR with IC50 of 1.7 nM. |
