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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Progesterone Receptor-Vilaprisan
Vilaprisan

Chemical Structure : Vilaprisan

CAS No.: 1262108-14-4

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Vilaprisan (BAY 1002670;BAY 10-02670)

货号: PC-63436Not For Human Use, Lab Use Only.

Vilaprisan (BAY 1002670) is a highly potent and selective progesterone receptor (PR) modulator (SPRM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Vilaprisan (BAY 1002670) is a highly potent and selective progesterone receptor (PR) modulator (SPRM).
    Vilaprisan exhibits marked efficacy in an innovative humanized fibroid disease model.
    Vilaprisan is a very promising treatment option for uterine fibroids.

    物理化学性质&存储条件

    分子量 544.577
    分子式 C27H29F5O4S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (8S,11R,13S,14S,17R)-17-hydroxy-13-methyl-11-(4-(methylsulfonyl)phenyl)-17-(perfluoroethyl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

    参考文献

    1. Wagenfeld A, et al. Hum Reprod. 2013 Aug;28(8):2253-64.

    2. Schütt B, et al. Hum Reprod. 2016 Aug;31(8):1703-12.

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