Cat. No. |
Product Name |
Information |
PC-42035 |
eFT508
MNK1/2 inhibitor
|
eFT508 (Tomivosertib) is a potent, highly selective, reversible, ATP-competitive, and orally bioavailable MNK1 and MNK2 inhibitor with IC50 of 1-2 nM in enzyme assays. |
PC-42633 |
CGP57380
MNK1 inhibitor
|
CGP57380 (CGP-57380) is a cell-permeable, specific MNK1 inhibitor with IC50 of 2.2 uM. |
PC-45112 |
Cercosporamide
MNK inhibitor
|
Cercosporamide is a broad-spectrum natural antifungal compound that acts as a selective and highly potent fungal Pkc1 kinase inhibitor, also inhibits Mnk inhibitor with IC50 of 116 nM and 11 nM for Mnk1 and Mnk2, respectively. |
PC-24273 |
MNK inhibitor EB1
MNK inhibitor
|
MNK inhibitor EB1 is potent inhibitor of inhibitor of MNK with IC50 of 0.69 uM (MNK1) and 9.4 uM (MNK2), most likely binds to the allosteric binding side adjacent to the ATP binding pocket. |
PC-24272 |
NUCC-0200808
MNK inhibitor
|
NUCC-0200808 is a potent selective, orally bioavailable inhibitor of mitogen-activated protein kinase (MAPK) interacting kinase MNK1 and MNK2 with IC50 of 42 nM and 29 nM, respectively. |