MEK(MAP2K) (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofMEK (MAP2K) MEK (MAP2K)

Cat. No.	Product Name	Information
PC-23993	Sinensetin MKK6 inhibitor	Sinensetin is a methylated flavonoid found in fruits that has strong anti-vascular and anti-inflammatory properties, sinensetin is a specific inhibitor of MKK6 with KD of 62 uM.
PC-42869	BIX02188	BIX02188 is a potent, selective inhibitor of MEK5 catalytic activity with IC50 of 4.3 nM, wekaly inhibits ERK5 catalytic activity (IC50=810 nM) and does not inhibits closely related kinases MEK1, MEK2, ERK2, and JNK2.
PC-63100	WX-554	WX-554 is an oral, small molecule allosteric inhibitor targeting mitogen-activated protein kinase kinase (MEK1 and MEK2) with an estimated IC50 of 4.7 and 10.7 nM, respectively.
PC-61420	Etacrynic acid	A loop diuretic used to treat high blood pressure and the swelling, a novel ligand and inhibitor of MAP2K6 kinase that inhibits MAP2K6 in part through alkylation of a nonconserved cysteine residue.
PC-42462	Refametinib R enantiomer	The R enantiomer of Refametinib, a potent, non–ATP-competitive, highly selective, allosteric inhibitor of MEK1/2 with IC50 of 19/47 nM respectively..
PC-42775	Trametinib DMSO solvate	A potent and highly specific MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM.

PREV 1 2 3 4 56NEXT