Refametinib R enantiomer |CAS:923032-38-6 Probechem Biochemicals

Chemical Structure : Refametinib R enantiomer

加入收藏

货号: PC-42462Not For Human Use, Lab Use Only.

The R enantiomer of Refametinib, a potent, non–ATP-competitive, highly selective, allosteric inhibitor of MEK1/2 with IC50 of 19/47 nM respectively..

获取报价单

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

The R enantiomer of Refametinib, a potent, non–ATP-competitive, highly selective, allosteric inhibitor of MEK1/2 with IC50 of 19/47 nM respectively.

分子量	572.3372
分子式	C19H20F3IN2O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO
Chemical Name/SMILES	Cyclopropanesulfonamide, N-[3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl]-1-[(2R)-2,3-dihydroxypropyl]-

1. Iverson C, et al. Cancer Res. 2009 Sep 1;69(17):6839-47.

2. Chang Q, et al. BMC Cancer. 2010 Sep 28;10:515.

3. Schmieder R, et al. Neoplasia. 2013 Oct;15(10):1161-71.