| Cat. No. |
Product Name |
Information |
| PC-21906 |
CC-99677
MAPKAPK2 (MK2) inhibitor
|
CC-99677 (Gamcemetinib, BMS-986371) is a potent, selective, covalent and orally bioavailable MAPKAPK2 (MK2) inhibitor with IC50 of 156.3 nM, potently inhibits HSP27 phosphorylation (pHSP27) with EC50 of 89 nM. |
| PC-38783 |
MMI-0100
MK2 inhibitor
|
MMI-0100 is a cell-permeant peptide inhibitor of MAPKAP kinase 2 (MK2), inhibits MK2 and downstream fibrosis and inflammation. |
| PC-38026 |
OUN11211
MK2 inhibitor
|
OUN11211 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2, MK2) with IC5 of 8.5 nM. |
| PC-35136 |
ATI-450
MK2 inhibitor
|
Zunsemetinib (ATI-450, CDD-450) is an unique inhibitor that selectively blocks p38α activation of proinflammatory kinase MAPK-MK2 while sparing p38α activation of PRAK and ATF2. |
| PC-43244 |
MK2-IN-1 hydrochloride
MK2 inhibitor
|
MK2-IN-1 is a potent, selecitve, non-ATP competitive MAPKAPK2 (MK2) inhibitor with IC50 of 0.11 uM. |
| PC-43243 |
MK2-IN-1
MK2 inhibitor
|
MK2-IN-1 is a potent, selecitve, non-ATP competitive MAPKAPK2(MK2) inhibitor with IC50 of 0.11 uM. |
| PC-70148 |
CMPD1
MK2 inhibitor
|
CMPD1 is a potent, selective, non-ATP-competitive inhibitor of p38α-mediated MAPK-activated protein kinase 2 (MK2, MAPKAPK2) phosphorylation with apparent Ki of 330 nM. |
| PC-70147 |
MK2 inhibitor III
MK2 inhibitor
|
MK2 inhibitor III (MK2-IN-3) is a potent, cell-permeable inhibitor of MAPKAPK2 (MK2) with IC50 of 8.5 nM. |
| PC-70144 |
MK2-IN-28
MK2/3 inhibitor
|
MK2-IN-28 is a potent and selective, non-ATP competitive, allosteric MAPKAPK2/3 (MK2/3) inhibitor with IC50 of 8 nM for MK2, hTNFα EC50 of 0.31 uM. |
| PC-70143 |
PF-3644022
MK2 inhibitor
|
PF-3644022 is a potent and selective, freely reversible, ATP-competitive inhibitor of MAPKAP2 (MK2) with Ki of 3 nM. |
