Chemical Structure : MMI-0100
CAS No.: 1039342-24-9
货号: PC-38783Not For Human Use, Lab Use Only.
MMI-0100 is a cell-permeant peptide inhibitor of MAPKAP kinase 2 (MK2), inhibits MK2 and downstream fibrosis and inflammation.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥1780 | In stock | |
10 mg | ¥2880 | In stock | |
25 mg | ¥4980 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
大包装,大折扣!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
MMI-0100 is a cell-permeant peptide inhibitor of MAPKAP kinase 2 (MK2), inhibits MK2 and downstream fibrosis and inflammation.
MMI-0100 prevents vein graft intimal thickening ex vivo and in vivo.
MMI-0100 inhibits cardiac fibrosis in myocardial infarction by direct actions on cardiomyocytes and fibroblasts via MK2 inhibition.
MMI-0100 treatment reduced cardiac fibrosis, decreased cardiac hypertrophy, and prolonged survival in fibrotic cMyBPC40k disease mice model.
分子量 | 2283.64 | |
分子式 | C98H171N37O26 | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
5 mM in PBS |
|
Chemical Name/SMILES |
L-Alanine, L-tyrosyl-L-alanyl-L-arginyl-L-alanyl-L-alanyl-L-alanyl-L-arginyl-L-glutaminyl-L-alanyl-L-arginyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-arginyl-L-glutaminyl-L-leucylglycyl-L-valyl-L-alanyl- |
1. Akihito Muto, et al. Vascul Pharmacol. Jan-Feb 2012;56(1-2):47-55.
2. Meng Q, et al. J Am Heart Assoc. 2017 Sep 4;6(9):e006590.
3. Xu L, et al. J Mol Cell Cardiol. 2014 Dec;77:86-101.
备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright