| Cat. No. |
Product Name |
Information |
| PC-22836 |
Epacadostat
IDO1 inhibitor
|
Epacadostat (INCB24360, INCB024360) is a hihgly potent and selective, oral bioavailable indoleamine-2,3-dioxygenase 1 (IDO1) inhibitor with IC50 of 73 nM. |
| PC-20021 |
Apoxidole-1
IDO1 inhibitor
|
Apoxidole-1 is a potent, selective type IV inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), Apoxidole-1 reduces cellular kynurenine (Kyn) levels with IC50 of 46.7 in HeLa cells, but does not inhibit IDO1 expression. |
| PC-49663 |
NLG802
IDO inhibitor
|
NLG-802 (NLG802) is a next-generation indoleamine-2,3-dioxygenase (IDO) pathway inhibitor and a prodrug of indoximod, shows increased oral bioavailability and maximum exposure. |
| PC-49659 |
LY3410738
mutant IDH1 inhibitor
|
LY3410738 (LY 3410738) is a potent, selective, and covalent inhibitor of mutant IDH1 (IDH1-R132), LY3410738 is more effective than Ivosidenib (Cat#PC-45550) and potentiates antileukemic activity of AML. |
| PC-73168 |
LY-3381916
IDO1 inhibitor
|
LY-3381916 is a potent, selective and brain-penetrant Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with IC50 of 7 nM. |
| PC-72378 |
BMS-986242
IDO1 inhibitor
|
BMS-986242 (BMS986242) is a potent, selective IDO1 inhibitor with IC50 of 2 nM in cellular IDO1 inhibition assays and IC50 of 25 nM in human whole blood (HWB) IDO1 inhibition assays. |
| PC-38081 |
PCC0208009
IDO inhibitor
|
PCC0208009 is a novel indoleamine 2,3-dioxygenase (IDO) inhibitor with IC50 of 4.52 nM at the cellular level. |
| PC-35777 |
VIS351
IDO1 inhibitor
|
VIS351 (VIS-351) is a potent activator of the immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated function of the IDO1 enzyme with Kd of 1.9 uM. |
| PC-35526 |
Roxyl-WL
IDO1 inhibitor
|
Roxyl-WL is a highly potent and selective inhibitor of IDO1 with IC50 of 1 nM. |
| PC-60068 |
BMS-986205
IDO1 inhibitor
|
BMS-986205 (Linrodostat, F-001287, ONO-7701) is a novel potent, selective and orally available IDO1 inhibitor with IC50 of 1.1 nM in cell-based assays. |
| PC-45552 |
Navoximod
IDO1 inhibitor
|
Navoximod (GDC-0919, NLG-919) is a potent, selective inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) with biochemical IC50 of 28 nM, and of Ki of 5.8 nM. |
| PC-46003 |
IDO-IN-1
IDO inhibitor
|
IDO-IN-1 is a potent, competitive indoleamine 2,3-dioxygenase (IDO) inhibitor with Hela IC50 of 19 nM. |
