PCC0208009 |CAS:1668565-74-9 Probechem Biochemicals

Chemical Structure : PCC0208009

CAS No.: 1668565-74-9

加入收藏

PCC0208009 (PCC 0208009, PCC-0208009)

货号: PC-38081Not For Human Use, Lab Use Only.

PCC0208009 is a novel indoleamine 2,3-dioxygenase (IDO) inhibitor with IC50 of 4.52 nM at the cellular level.

规格	价格	库存
10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

PCC0208009 is a novel indoleamine 2,3-dioxygenase (IDO) inhibitor with IC50 of 4.52 nM at the cellular level.
PCC0208009 is a highly effective IDO inhibitor, not only directly inhibiting IDO activity but also participating in the gene regulation of IDO expression at the transcription and translation levels.
PCC0208009 significantly enhanced the anti-tumor effects of temozolomide in GL261 and C6 models, by increasing the percentages of CD3+, CD4+, and CD8+ T cells within tumors and suppressing tumor proliferation.
PCC0208009 alleviates neuropathic pain and co-morbidities by regulating synaptic plasticity of ACC and amygdala.

物理化学性质&存储条件

分子量	497.647
分子式	C29H35N7O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Urea, N-[4-[bis(2-methylpropyl)amino]-2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]-N'-(4-methylphenyl)-

参考文献

1. Sun S, et al. Int J Immunopathol Pharmacol. 2018 Jan-Dec;32:2058738418787991.

2. Wang Y, et al. Biochem Pharmacol. 2020 Jul;177:113926.

PCC0208009 (PCC 0208009, PCC-0208009)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

PCC0208009 (PCC 0208009, PCC-0208009)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.