| Cat. No. |
Product Name |
Information |
| PC-49656 |
AVN-944
IMPDH inhibitor
|
AVN-944 (VX-944) is a potent, selective, noncompetitive inhibitor of both human inosine 5-monophosphate dehydrogenase (IMPDH) isoforms (Ki=6-10 nM). |
| PC-49653 |
FF-10501
IMPDH inhibitor
|
FF-10501 (SM-108, Bredinin aglycone) is a small molecule inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH), maintained cell growth inhibitory activities in the azacitidine-resistant cell lines. |
| PC-35012 |
VX-148
IMPDH inhibitor
|
VX-148 (VX148) is a potent, uncompetitive, orally bioavailable IMPDH inhibitor with Ki of 6 nM against IMPDH type II enzyme. |
| PC-35011 |
Merimepodib
IMPDH inhibitor
|
Merimepodib (VX-497, VI-21497, MMPD) is a potent, selective, reversible, uncompetitive IMPDH inhibitor with broad-spectrum antiviral activity. |
| PC-61690 |
FF-10501-01
IMPDH inhibitor
|
FF-10501-01 is a potent, selective and orally available IMPDH inhibitor. |
| PC-70216 |
Sappanone A
IMPDH2 inhibitor
|
Sappanone A is a homoisoflavanone found in Caesalpinia sappan, a potent, selective IMPDH2 inhibitor that covalently binds to Cys140 with Kd of 3.944 nM, almost 10 times lower than the Kd of binding to IMPDH1. |
| PC-70215 |
IMPDH2-IN-5
IMPDH2 inhibitor
|
IMPDH2-IN-5 is a potent, selective IMPDH2 inhibitor that covalently binds to Cys140 with IC50 of 620 nM (inhibition of NO production). |
| PC-24266 |
Mycophenolate mofetil
IMPDH inhibitor
|
Mycophenolate mofetil (RS61443) is the morpholinoethylester proagent of Mycophenolic acid and inhibitor de novo purine synthesis via inhibition of inosine monophosphate dehydrogenase (IMPDH). |
