FF-10501-01

首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-IMPDH-FF-10501-01

Chemical Structure : FF-10501-01

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货号: PC-61690Not For Human Use, Lab Use Only.

FF-10501-01 is a potent, selective and orally available IMPDH inhibitor.

规格	价格	库存	数量
25 mg		Get quote
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100 mg		Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

FF-10501-01 is a potent, selective and orally available IMPDH inhibitor.
FF-10501-01 effectively induces AML cell death and reduces AML peripheral blood cell proliferation (mean IC50=14.6 uM) by targeting guanine nucleotide biosynthesis regardless of HMA resistance status.

物理化学性质&存储条件

分子量	562.45
分子式	C4H5N3O2.3/4H2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Imidazole-4-carboxamide, 5-hydroxy-, hydrate (4:3)

参考文献

1. Yang H, et al. Leuk Res. 2017 Aug;59:85-92.

2. Murase M, et al. Pharmacol Res Perspect. 2016 Jan 28;4(1):e00206.

3. Ichii M, et al. Leuk Lymphoma. 2017 Jul 21:1-12.

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FF-10501-01

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