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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-IMPDH-Mycophenolic acid
Mycophenolic acid

Chemical Structure : Mycophenolic acid

CAS No.: 24280-93-1

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Mycophenolic acid (Mycophenolate)

货号: PC-28222Not For Human Use, Lab Use Only.

Mycophenolic acid (MPA, Mycophenolate) is a potent, specific, reversible inosine monophosphate dehydrogenase (IMPDH) inhibitor with EC50 of 0.24 uM, inhibits de-novo purine synthesis required for nucleotide base formation, shows antifungal, antibacterial, and immunosuppressive properties.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Mycophenolic acid (MPA, Mycophenolate) is a potent, specific, reversible inosine monophosphate dehydrogenase (IMPDH) inhibitor with EC50 of 0.24 uM, inhibits de-novo purine synthesis required for nucleotide base formation, shows antifungal, antibacterial, and immunosuppressive properties.

物理化学性质&存储条件

分子量 320.34
分子式 C17H20O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid

参考文献

1. Lee HJ, et al. Cancer Res. 1985 Nov;45(11 Pt 1):5512-20.

2. Collart FR, et al. Mol Cell Biol. 1987 Sep;7(9):3328-31.

3. Sophie Domhan, et al. Mol Cancer Ther. 2008 Jun;7(6):1656-68.

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