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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-IMPDH-IMPDH2-IN-5
IMPDH2-IN-5

Chemical Structure : IMPDH2-IN-5

CAS No.: 2119603-25-5

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IMPDH2-IN-5 (IMPDH2 inhibitor)

货号: PC-70215Not For Human Use, Lab Use Only.

IMPDH2-IN-5 is a potent, selective IMPDH2 inhibitor that covalently binds to Cys140 with IC50 of 620 nM (inhibition of NO production).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    IMPDH2-IN-5 is a potent, selective IMPDH2 inhibitor that covalently binds to Cys140 with IC50 of 620 nM (inhibition of NO production).
    IMPDH2-IN-5 is a Sappanone A derivative.

    物理化学性质&存储条件

    分子量 302.257
    分子式 C16H11FO5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (E)-3-(3,4-dihydroxybenzylidene)-5-fluoro-7-hydroxychroman-4-one

    参考文献

    1. Liao LX, et al. Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5986-E5994.

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