| Cat. No. |
Product Name |
Information |
| PC-60167 |
GPR120 agonist 4x
GPR120 (FFAR4) agonist
|
GPR120 agonist 4x is a potent, selective, orally bioavailable GPR120 agonist with EC50 of 42 nM in calcium flux assays. |
| PC-70042 |
DC260126
GPR40 agonist
|
DC260126 is a potent GPR40 (FFAR1) agonist with IC50 of 6.28 uM for inhibition of Ca2+ stimulated by linoleic acid. |
| PC-42610 |
TAK-875
GPR40 agonist
|
TAK-875 (Fasiglifam) is a potent, selective, orally bioavailable GPR40 (FFA1) agonist with EC50 of 14 nM. |
| PC-42283 |
TUG-891
GPR120 agonist
|
TUG-891 (TUG891) is a potent, selective human GPR120 (FFA4) agonist with pEC50 of 7.22. |
| PC-45843 |
GW-1100
GPR40 inhibitor
|
GW-1100 (SB-376752) is a potent, selective GPR40 antagonist that dose dependently inhibits GPR40-mediated Ca2+ elevations stimulated by GW9508 and linoleic acid with pIC50 of 5.99. |
| PC-45779 |
GSK137647A
GPR120 (FFAR4) agonist
|
GSK-137647 (GSK-137647A) is a potent, selective GPR120 (FFA4) agonist with pEC50 of 6.3, >100-fold selectivity over the FFA1, FFA2, and FFA3 receptors. |
| PC-42400 |
GPR120 agonist 1
GPR120 (FFAR4) agonist
|
GPR120 agonist 1 is a potent, fully selective, orally available GPR120 (FFA4) agonist with pEC50 of 7.62. |
| PC-43813 |
AMG 837
GPR40 agonist
|
AMG 837 is a potent partial GPR40 (FFA1) agonist (EC50=13 nM for hGPR40). |
| PC-24798 |
TUG-1958
GPR43 antagonist
|
TUG-1958 is a potent, selective antagonist of GPR43 (FFA2R, free fatty acid receptor 2) with pIC50 of 7.41 uM (hFFA2) in [35S]GTPγS-based binding assays. |
| PC-24797 |
BTI-A-404
hGPR43 antagonist
|
BTI-A-404 is a selective and potent competitive inverse agonist / antagonist of human GPR43 (FFA2R) with cAMP IC50 of 9.5 uM. |
| PC-24796 |
CATPB
FFA2 antagonist
|
CATPB is a potent, selective free fatty acid receptor 2 (FFA2R, GPR43) antagonist with cAMP pIC50 of 6.96 and GTPγS pIC50 of 6.68, shows inverse agonist properties. |
| PC-24795 |
GPR43 agonist compound 187
GPR43 agonist
|
GPR43 agonist compound 187 is a potent, selective GPR43 (FFAR2 or FFA2) agonist, induces Rho GTPase signaling to activate YAP/TAZ, causes YAP/TAZ accumulated in the nucleus in GPR43-expressing HEK293 cells in a manner dependent on Gα12/13 and Gαq/11. |
