TUG-891 |CAS:1374516-07-0 Probechem Biochemicals

Chemical Structure : TUG-891

CAS No.: 1374516-07-0

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TUG-891 (TUG891)

货号: PC-42283Not For Human Use, Lab Use Only.

TUG-891 is a potent, selective human GPR120 (FFA4) agonist with pEC50 of 7.22.

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10 mg	￥1280	In stock
25 mg	￥1980	In stock
50 mg	￥2880	In stock
100 mg		Get quote

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生物&药学活性

TUG-891 is a potent, selective human GPR120 (FFA4) agonist with pEC50 of 7.22.
TUG-891 displays 288-fold more potent than hFFA1.
TUG-891 stimulates GLP-1 secretion from enteroendocrine cells, enhances glucose uptake in 3T3-L1 adipocytes, and inhibitis release of proinflammatory mediators from RAW264.7 macrophages.
TUG-891 inhibits LPA- and EGF-induced proliferation and migration in DU145 and PC-3 cells.

物理化学性质&存储条件

分子量	364.4094432
分子式	C23H21FO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzenepropanoic acid, 4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]-

参考文献

1. Shimpukade B, et al. J Med Chem. 2012 May 10;55(9):4511-5.

2. Hudson BD, et al. Mol Pharmacol. 2013 Nov;84(5):710-25.

3. Liu Z, et al. J Pharmacol Exp Ther. 2015 Feb;352(2):380-94.

TUG-891 (TUG891)

生物&药学活性

物理化学性质&存储条件

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TUG-891 (TUG891)

生物&药学活性

物理化学性质&存储条件

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